Monthly Archives: March 2013
In the alpha helix, the amino acids arrange in a helical formation, with 3.6 amino acid residues per turn of the helix. The carbonyl oxygen of each peptide is hydrogen bonded to the hydrogen of the amino group of an … Continue reading
As shown earlier in this blog, amino acids serve as building blocks for polypeptide chains which, in turn assemble to form protein structures. Proteins are the most abundant and functionally diverse molecules in living systems; some of these roles include … Continue reading
The organophosphate malathion bind irreversbly to cholinesterase, which is responsible for the hydrolysis of the neurotransmitter acetylcholine in the synaptic cleft. Primarily used as an insecticide in agriculture, it also has uses as medical treatment in low doses for head … Continue reading
David E. Green was an American biochemist who dedicated his life’s work to the study of enzymes but particularly the electron transport chain and oxidative phosphorylation. At the University of Cambridge he worked on redox reaction applications in biological systems … Continue reading
Petroski, Matthew. 2008. The Ubiquitin System, Disease and Drug Discovery. Accessed March 29th 2013. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582801/ THE UBIQUITIN SYSTEM, DISEASE AND DRUG RECOVERY The ubiquitin system, as its name suggests, controls a host of cellular processes via activation of ubiquitin(UB) … Continue reading
Nobel Prize Winner Medicine or Physiology (1964). Was a prominent German American biochemist whose research into fatty acid and cholesterol metabolism earned him the coveted award. He showed that all natural steroid-related substances in humans are synthesized from cholesterol.He also … Continue reading
A peptide bond is covalent in nature and is formed via the interaction of the carboxyl group of one amino acid with the amino group of another in a condensation reaction.